| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 28-1-27 21:00 | 1899 Hoffenheim | Ferencvárosi TC | -:- |
| 28-1-27 21:00 | Omonia Nicosia | Besiktas Istanbul | -:- |
| 28-1-27 21:00 | NK Celje | NEC Nijmegen | -:- |
| 28-1-27 21:00 | AFC Bournemouth | Hapoel Beër Sjeva | -:- |
| 28-1-27 21:00 | Viktoria Pilsen | Jagiellonia Białystok | -:- |
| 28-1-27 21:00 | Royale Union Saint-Gilloise | Celtic Glasgow | -:- |
| 28-1-27 21:00 | Olympique Marseille | RSC Anderlecht | -:- |
| 28-1-27 21:00 | Olympique Lyon | Bayer 04 Leverkusen | -:- |
| 28-1-27 21:00 | Sparta Prag | Stade Rennes | -:- |
| 28-1-27 21:00 | FC Red Bull Salzburg | Crystal Palace | -:- |
| 28-1-27 21:00 | Dinamo Zagreb | SK Sturm Graz | -:- |
| 28-1-27 21:00 | Juventus Turin | Real Sociedad | -:- |
| 28-1-27 21:00 | Benfica Lissabon | AZ Alkmaar | -:- |
| 28-1-27 21:00 | AC Mailand | FC Ararat-Armenia | -:- |
| 28-1-27 21:00 | OFI Crete | Lech Poznan | -:- |
| 28-1-27 21:00 | Celta Vigo | Lillestroem SK | -:- |
| 28-1-27 21:00 | AFC Sunderland | Levski Sofia | -:- |
| 28-1-27 21:00 | SCU Torreense | Olympiakos Piräus | -:- |