Speelschema
| Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|
| 14-12-21 18:30 | 14-12-21 18:30 | VfB Stuttgart | FC Bayern München | 0:5 | 8 - 8 - 2 |
| 14-12-21 20:30 | 14-12-21 20:30 | Arminia Bielefeld | VfL Bochum | 2:0 | 4 - 4 - 3 |
| 14-12-21 20:30 | 14-12-21 20:30 | FSV Mainz 05 | Hertha BSC | 4:0 | 2 - 5 - 7 |
| 14-12-21 20:30 | 14-12-21 20:30 | VfL Wolfsburg | 1. FC Köln | 2:3 | 3 - 3 - 6 |
| 15-12-21 18:30 | 15-12-21 18:30 | Bor. Mönchengladbach | Eintracht Frankfurt | 2:3 | 3 - 5 - 3 |
| 15-12-21 20:30 | 15-12-21 20:30 | FC Augsburg | RB Leipzig | 1:1 | 8 - 8 - 2 |
| 15-12-21 20:30 | 15-12-21 20:30 | 1. FC Union Berlin | SC Freiburg | 0:0 | 4 - 4 - 4 |
| 15-12-21 20:30 | 15-12-21 20:30 | Bayer 04 Leverkusen | 1899 Hoffenheim | 2:2 | 2 - 5 - 7 |
| 15-12-21 20:30 | 15-12-21 20:30 | Borussia Dortmund | SpVgg Greuther Fürth | 3:0 | 2 - 8 - 8 |