Speelschema
| Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|
| 2-10-21 13:30 | 2-10-21 13:30 | Manchester United | FC Everton | 1:1 | 2 - 5 punten |
| 2-10-21 16:00 | 2-10-21 16:00 | Leeds United | FC Watford | 1:0 | 2 - 5 punten |
| 2-10-21 16:00 | 2-10-21 16:00 | Wolverhampton Wanderers | Newcastle United | 2:1 | 2 - 5 punten |
| 2-10-21 16:00 | 2-10-21 16:00 | FC Burnley | Norwich City | 0:0 | 2 - 5 punten |
| 2-10-21 16:00 | 2-10-21 16:00 | FC Chelsea | FC Southampton | 3:1 | 2 - 5 punten |
| 2-10-21 18:30 | 2-10-21 18:30 | Brighton and Hove Albion | FC Arsenal | 0:0 | 2 - 5 punten |
| 3-10-21 15:00 | 3-10-21 15:00 | Crystal Palace | Leicester City | 2:2 | 2 - 5 punten |
| 3-10-21 15:00 | 3-10-21 15:00 | Tottenham Hotspur | Aston Villa | 2:1 | 2 - 5 punten |
| 3-10-21 15:00 | 3-10-21 15:00 | West Ham United | Brentford FC | 1:2 | 2 - 5 punten |
| 3-10-21 17:30 | 3-10-21 17:30 | FC Liverpool | Manchester City | 2:2 | 2 - 5 punten |