Speelschema
| Competitie | Termijn | Voorspellingsdeadline | Thuis | Uitteam | Uitslag | Puntentelling |
|---|---|---|---|---|---|---|
| 2.BL | 17-9-21 18:30 | 17-9-21 18:30 | 1. FC Nürnberg | FC Hansa Rostock | 1:0 | 2 - 7 - 7 |
| 2.BL | 17-9-21 18:30 | 17-9-21 18:30 | FC Schalke 04 | Karlsruher SC | 1:2 | 2 - 7 - 7 |
| 2.BL | 18-9-21 13:30 | 18-9-21 13:30 | Fortuna Düsseldorf | Jahn Regensburg | 1:1 | 3 - 3 - 4 |
| 2.BL | 18-9-21 13:30 | 18-9-21 13:30 | SV Sandhausen | 1. FC Heidenheim 1846 | 1:3 | 4 - 4 - 3 |
| 2.BL | 18-9-21 13:30 | 18-9-21 13:30 | Holstein Kiel | Hannover 96 | 0:3 | 3 - 7 - 3 |
| 2.BL | 18-9-21 20:30 | 18-9-21 20:30 | Werder Bremen | Hamburger SV | 0:2 | 2 - 7 - 7 |
| 2.BL | 19-9-21 13:30 | 19-9-21 13:30 | SV Darmstadt 98 | Dynamo Dresden | 1:0 | 2 - 4 - 7 |
| 2.BL | 19-9-21 13:30 | 19-9-21 13:30 | FC St. Pauli | FC Ingolstadt | 4:1 | 2 - 7 - 7 |
| 2.BL | 19-9-21 13:30 | 19-9-21 13:30 | Erzgebirge Aue | SC Paderborn 07 | 1:4 | 7 - 7 - 2 |