| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 24-10-25 20:30 | Modena FC | FC Empoli | 2:1 |
| 25-10-25 15:00 | Sampdoria Genua | Frosinone Calcio | 1:1 |
| 25-10-25 15:00 | FC Südtirol | FC Cesena | 0:1 |
| 25-10-25 15:00 | AC Monza | AC Reggiana 1919 | 3:1 |
| 25-10-25 15:00 | US Avellino | Spezia Calcio | 0:4 |
| 25-10-25 15:00 | Virtus Entella | Pescara Calcio | 1:1 |
| 25-10-25 17:15 | Carrarese Calcio 1908 | Venezia FC | 3:2 |
| 25-10-25 19:30 | US Catanzaro 1929 | Palermo FC | 1:0 |
| 26-10-25 15:00 | Padova Calcio | Juve Stabia | 2:2 |
| 26-10-25 17:15 | SSC Bari | Mantova 1911 | 1:0 |
| 28-10-25 18:30 | US Lecce | SSC Neapel | -:- |
| 28-10-25 20:45 | Atalanta Bergamo | AC Mailand | -:- |
| 29-10-25 18:30 | Como Calcio | Hellas Verona | -:- |
| 29-10-25 18:30 | Juventus Turin | Udinese Calcio | -:- |
| 29-10-25 18:30 | AS Rom | Parma Calcio 1913 | -:- |
| 29-10-25 20:45 | FC Bologna | FC Turin | -:- |
| 29-10-25 20:45 | Inter Mailand | AC Florenz | -:- |
| 29-10-25 20:45 | Genua CFC | US Cremonese | -:- |
| 30-10-25 18:30 | Cagliari Calcio | Sassuolo Calcio | -:- |
| 30-10-25 20:45 | Pisa Sporting Club | Lazio Rom | -:- |