| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 9-8-25 20:30 | Virtus Entella | Ternana Calcio | 4:0 |
| 10-8-25 19:30 | Padova Calcio | Vicenza Calcio | 0:2 |
| 10-8-25 20:30 | US Avellino | Audace Cerignola | 0:1 |
| 10-8-25 20:30 | Pescara Calcio | Rimini FC | 1:0 |
| 15-8-25 18:00 | FC Empoli | AC Reggiana 1919 | 4:1n.p./1:190m |
| 15-8-25 18:30 | Sassuolo Calcio | US Catanzaro 1929 | 1:0 |
| 15-8-25 20:45 | US Lecce | Juve Stabia | 2:0 |
| 15-8-25 21:15 | Genua CFC | Vicenza Calcio | 3:0 |
| 16-8-25 18:00 | Venezia FC | Mantova 1911 | 4:0 |
| 16-8-25 18:30 | Como Calcio | FC Südtirol | 3:1 |
| 16-8-25 20:45 | Cagliari Calcio | Virtus Entella | 6:5n.p./1:190m |
| 16-8-25 21:15 | US Cremonese | Palermo FC | 4:5n.p./0:090m |
| 17-8-25 18:00 | AC Monza | Frosinone Calcio | 0:1 |
| 17-8-25 18:30 | Parma Calcio 1913 | Pescara Calcio | 2:0 |
| 17-8-25 20:45 | FC Cesena | Pisa Sporting Club | 1:2n.p./0:090m |
| 17-8-25 21:15 | AC Mailand | SSC Bari | 2:0 |
| 18-8-25 18:00 | Audace Cerignola | Hellas Verona | 3:5n.p./1:190m |
| 18-8-25 18:30 | Spezia Calcio | Sampdoria Genua | 5:3n.p./1:190m |
| 18-8-25 20:45 | Udinese Calcio | Carrarese Calcio 1908 | 2:0 |
| 18-8-25 21:15 | FC Turin | Modena FC | 1:0 |
| 22-8-25 20:30 | Pescara Calcio | FC Cesena | 1:3 |
| 23-8-25 18:30 | Genua CFC | US Lecce | 0:0 |
| 23-8-25 18:30 | Sassuolo Calcio | SSC Neapel | 0:2 |
| 23-8-25 19:00 | Virtus Entella | Juve Stabia | 1:1 |
| 23-8-25 19:00 | FC Empoli | Padova Calcio | 3:1 |
| 23-8-25 20:45 | AC Mailand | US Cremonese | 1:2 |
| 23-8-25 20:45 | AS Rom | FC Bologna | 1:0 |
| 23-8-25 21:00 | AC Monza | Mantova 1911 | 1:0 |
| 23-8-25 21:00 | Palermo FC | AC Reggiana 1919 | 2:1 |
| 24-8-25 18:30 | Como Calcio | Lazio Rom | 2:0 |
| 24-8-25 18:30 | Cagliari Calcio | AC Florenz | 1:1 |
| 24-8-25 19:00 | Spezia Calcio | Carrarese Calcio 1908 | 0:2 |
| 24-8-25 19:00 | Venezia FC | SSC Bari | 2:1 |
| 24-8-25 20:45 | Atalanta Bergamo | Pisa Sporting Club | 1:1 |
| 24-8-25 20:45 | Juventus Turin | Parma Calcio 1913 | 2:0 |
| 24-8-25 21:00 | Frosinone Calcio | US Avellino | 2:0 |
| 24-8-25 21:00 | US Catanzaro 1929 | FC Südtirol | 1:1 |
| 25-8-25 18:30 | Udinese Calcio | Hellas Verona | 1:1 |
| 25-8-25 20:30 | Sampdoria Genua | Modena FC | 0:2 |
| 25-8-25 20:45 | Inter Mailand | FC Turin | 5:0 |