| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 28-10-25 20:30 | Frosinone Calcio | Virtus Entella | 4:0 |
| 28-10-25 20:30 | FC Cesena | Carrarese Calcio 1908 | 2:1 |
| 28-10-25 20:30 | FC Empoli | Sampdoria Genua | 1:1 |
| 28-10-25 20:30 | Pescara Calcio | US Avellino | 1:1 |
| 28-10-25 20:30 | AC Reggiana 1919 | Modena FC | 1:0 |
| 28-10-25 20:30 | Palermo FC | AC Monza | 0:3 |
| 29-10-25 20:30 | Mantova 1911 | US Catanzaro 1929 | 1:3 |
| 29-10-25 20:30 | Spezia Calcio | Padova Calcio | 1:1 |
| 29-10-25 20:30 | Venezia FC | FC Südtirol | 3:0 |
| 1-11-25 15:00 | Udinese Calcio | Atalanta Bergamo | 1:0 |
| 1-11-25 18:00 | SSC Neapel | Como Calcio | 0:0 |
| 1-11-25 20:45 | US Cremonese | Juventus Turin | 1:2 |
| 2-11-25 12:30 | Hellas Verona | Inter Mailand | 1:2 |
| 2-11-25 15:00 | AC Florenz | US Lecce | 0:1 |
| 2-11-25 15:00 | FC Turin | Pisa Sporting Club | 2:2 |
| 2-11-25 18:00 | Parma Calcio 1913 | FC Bologna | 1:3 |
| 2-11-25 20:45 | AC Mailand | AS Rom | 1:0 |
| 3-11-25 18:30 | Sassuolo Calcio | Genua CFC | 1:2 |
| 3-11-25 20:45 | Lazio Rom | Cagliari Calcio | 2:0 |
| 4-12-25 19:30 | Juve Stabia | SSC Bari | 0:0 |