| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 21-11-25 20:30 | US Catanzaro 1929 | Pescara Calcio | 3:3 |
| 22-11-25 15:00 | US Avellino | FC Empoli | 0:3 |
| 22-11-25 15:00 | Virtus Entella | Palermo FC | 1:1 |
| 22-11-25 15:00 | Carrarese Calcio 1908 | AC Reggiana 1919 | 0:0 |
| 22-11-25 17:15 | Padova Calcio | Venezia FC | 0:2 |
| 22-11-25 19:30 | SSC Bari | Frosinone Calcio | 2:3 |
| 23-11-25 15:00 | Mantova 1911 | Spezia Calcio | 4:1 |
| 23-11-25 15:00 | Modena FC | FC Südtirol | 0:0 |
| 23-11-25 17:15 | AC Monza | FC Cesena | 1:0 |
| 24-11-25 20:30 | Sampdoria Genua | Juve Stabia | 1:0 |
| 28-11-25 20:45 | Como Calcio | Sassuolo Calcio | 2:0 |
| 29-11-25 15:00 | Genua CFC | Hellas Verona | 2:1 |
| 29-11-25 15:00 | Parma Calcio 1913 | Udinese Calcio | 0:2 |
| 29-11-25 18:00 | Juventus Turin | Cagliari Calcio | 2:1 |
| 29-11-25 20:45 | AC Mailand | Lazio Rom | 1:0 |
| 30-11-25 12:30 | US Lecce | FC Turin | 2:1 |
| 30-11-25 15:00 | Pisa Sporting Club | Inter Mailand | 0:2 |
| 30-11-25 18:00 | Atalanta Bergamo | AC Florenz | 2:0 |
| 30-11-25 20:45 | AS Rom | SSC Neapel | 0:1 |
| 1-12-25 20:45 | FC Bologna | US Cremonese | 1:3 |