| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 8-12-25 20:30 | US Avellino | Venezia FC | -:- |
| 8-12-25 20:30 | SSC Bari | Pescara Calcio | -:- |
| 8-12-25 20:30 | Frosinone Calcio | Juve Stabia | -:- |
| 8-12-25 20:30 | Mantova 1911 | AC Reggiana 1919 | -:- |
| 8-12-25 20:30 | FC Empoli | Palermo FC | -:- |
| 8-12-25 20:30 | Virtus Entella | Spezia Calcio | -:- |
| 8-12-25 20:30 | Padova Calcio | FC Cesena | -:- |
| 8-12-25 20:30 | Sampdoria Genua | Carrarese Calcio 1908 | -:- |
| 8-12-25 20:30 | Modena FC | US Catanzaro 1929 | -:- |
| 8-12-25 20:30 | AC Monza | FC Südtirol | -:- |
| 14-12-25 18:00 | FC Bologna | Juventus Turin | -:- |
| 14-12-25 18:00 | Atalanta Bergamo | Cagliari Calcio | -:- |
| 14-12-25 18:00 | Genua CFC | Inter Mailand | -:- |
| 14-12-25 18:00 | AC Florenz | Hellas Verona | -:- |
| 14-12-25 18:00 | AC Mailand | Sassuolo Calcio | -:- |
| 14-12-25 18:00 | US Lecce | Pisa Sporting Club | -:- |
| 14-12-25 18:00 | AS Rom | Como Calcio | -:- |
| 14-12-25 18:00 | Parma Calcio 1913 | Lazio Rom | -:- |
| 14-12-25 18:00 | Udinese Calcio | SSC Neapel | -:- |
| 14-12-25 18:00 | FC Turin | US Cremonese | -:- |