| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 20-9-25 15:00 | Spezia Calcio | Juve Stabia | -:- |
| 20-9-25 15:00 | Venezia FC | FC Cesena | -:- |
| 20-9-25 15:00 | Mantova 1911 | Modena FC | -:- |
| 20-9-25 15:00 | AC Monza | Sampdoria Genua | -:- |
| 20-9-25 15:00 | Carrarese Calcio 1908 | US Avellino | -:- |
| 20-9-25 15:00 | Frosinone Calcio | FC Südtirol | -:- |
| 20-9-25 15:00 | Pescara Calcio | FC Empoli | -:- |
| 20-9-25 15:00 | AC Reggiana 1919 | US Catanzaro 1929 | -:- |
| 20-9-25 15:00 | Padova Calcio | Virtus Entella | -:- |
| 20-9-25 15:00 | Palermo FC | SSC Bari | -:- |
| 21-9-25 18:00 | AC Florenz | Como Calcio | -:- |
| 21-9-25 18:00 | US Cremonese | Parma Calcio 1913 | -:- |
| 21-9-25 18:00 | Lazio Rom | AS Rom | -:- |
| 21-9-25 18:00 | Inter Mailand | Sassuolo Calcio | -:- |
| 21-9-25 18:00 | SSC Neapel | Pisa Sporting Club | -:- |
| 21-9-25 18:00 | US Lecce | Cagliari Calcio | -:- |
| 21-9-25 18:00 | Udinese Calcio | AC Mailand | -:- |
| 21-9-25 18:00 | FC Turin | Atalanta Bergamo | -:- |
| 21-9-25 18:00 | FC Bologna | Genua CFC | -:- |
| 21-9-25 18:00 | Hellas Verona | Juventus Turin | -:- |