| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 27-9-25 15:00 | US Avellino | Virtus Entella | -:- |
| 27-9-25 15:00 | SSC Bari | Sampdoria Genua | -:- |
| 27-9-25 15:00 | FC Empoli | Carrarese Calcio 1908 | -:- |
| 27-9-25 15:00 | Mantova 1911 | Frosinone Calcio | -:- |
| 27-9-25 15:00 | US Catanzaro 1929 | Juve Stabia | -:- |
| 27-9-25 15:00 | FC Cesena | Palermo FC | -:- |
| 27-9-25 15:00 | FC Südtirol | AC Reggiana 1919 | -:- |
| 27-9-25 15:00 | Venezia FC | Spezia Calcio | -:- |
| 27-9-25 15:00 | Modena FC | Pescara Calcio | -:- |
| 27-9-25 15:00 | AC Monza | Padova Calcio | -:- |
| 28-9-25 18:00 | Juventus Turin | Atalanta Bergamo | -:- |
| 28-9-25 18:00 | Genua CFC | Lazio Rom | -:- |
| 28-9-25 18:00 | AC Mailand | SSC Neapel | -:- |
| 28-9-25 18:00 | US Lecce | FC Bologna | -:- |
| 28-9-25 18:00 | Pisa Sporting Club | AC Florenz | -:- |
| 28-9-25 18:00 | Parma Calcio 1913 | FC Turin | -:- |
| 28-9-25 18:00 | Sassuolo Calcio | Udinese Calcio | -:- |
| 28-9-25 18:00 | AS Rom | Hellas Verona | -:- |
| 28-9-25 18:00 | Como Calcio | US Cremonese | -:- |
| 28-9-25 18:00 | Cagliari Calcio | Inter Mailand | -:- |