| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 17-10-25 20:30 | Virtus Entella | Sampdoria Genua | 3:1 |
| 18-10-25 15:00 | Frosinone Calcio | AC Monza | 0:1 |
| 18-10-25 15:00 | Pescara Calcio | Carrarese Calcio 1908 | 2:2 |
| 18-10-25 15:00 | Mantova 1911 | FC Südtirol | 1:1 |
| 18-10-25 15:00 | AC Reggiana 1919 | SSC Bari | 3:1 |
| 18-10-25 17:15 | Juve Stabia | US Avellino | 2:0 |
| 18-10-25 19:30 | Spezia Calcio | FC Cesena | 1:2 |
| 19-10-25 15:00 | Palermo FC | Modena FC | 1:1 |
| 19-10-25 17:15 | FC Empoli | Venezia FC | 1:1 |
| 19-10-25 19:30 | US Catanzaro 1929 | Padova Calcio | 0:1 |
| 24-10-25 20:45 | AC Mailand | Pisa Sporting Club | 2:2 |
| 25-10-25 15:00 | Parma Calcio 1913 | Como Calcio | 0:0 |
| 25-10-25 15:00 | Udinese Calcio | US Lecce | 3:2 |
| 25-10-25 18:00 | SSC Neapel | Inter Mailand | 3:1 |
| 25-10-25 20:45 | US Cremonese | Atalanta Bergamo | 1:1 |
| 26-10-25 12:30 | FC Turin | Genua CFC | 2:1 |
| 26-10-25 15:00 | Sassuolo Calcio | AS Rom | 0:1 |
| 26-10-25 15:00 | Hellas Verona | Cagliari Calcio | 2:2 |
| 26-10-25 18:00 | AC Florenz | FC Bologna | 2:2 |
| 26-10-25 20:45 | Lazio Rom | Juventus Turin | 1:0 |