| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 5-12-25 20:30 | Salford City | Leyton Orient | 4:0 |
| 6-12-25 16:00 | Exeter City | Wycombe Wanderers | 4:0 |
| 6-12-25 16:00 | Cheltenham Town | Buxton FC | 6:2 |
| 6-12-25 16:00 | Accrington Stanley | Mansfield Town | 3:5n.p. |
| 6-12-25 16:00 | Stockport County FC | Cambridge United | 4:5n.p. |
| 6-12-25 16:00 | Milton Keynes Dons FC | Oldham Athletic | 3:1 |
| 6-12-25 16:00 | Wigan Athletic | Barrow FC | 6:5n.p. |
| 6-12-25 16:00 | Fleetwood Town | Luton Town | 6:4n.p. |
| 6-12-25 16:00 | Swindon Town | Bolton Wanderers | 4:0 |
| 6-12-25 16:00 | Chelmsford City | Weston-Super-Mare | 0:2 |
| 6-12-25 16:00 | Peterborough United | FC Barnsley | 0:1 |
| 6-12-25 16:00 | Grimsby Town | Wealdstone FC | 4:0 |
| 6-12-25 16:00 | FC Port Vale | Bristol Rovers | 1:0 |
| 6-12-25 18:15 | Sutton United | Shrewsbury Town | 1:2n.v. |
| 6-12-25 20:30 | FC Chesterfield | Doncaster Rovers | 1:2 |
| 7-12-25 13:30 | Slough Town FC | Macclesfield FC | -:- |
| 7-12-25 15:30 | Boreham Wood | Newport County | -:- |
| 7-12-25 16:30 | FC Gateshead | FC Walsall | -:- |
| 7-12-25 18:30 | FC Blackpool | Carlisle United | -:- |
| 8-12-25 20:30 | Brackley Town | Burton Albion | -:- |