| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 13-5-23 19:00 | Chicago Fire | St. Louis City SC | 1:0 |
| 14-5-23 1:30 | Columbus Crew | Orlando City | 2:2 |
| 14-5-23 1:30 | Atlanta United FC | Charlotte FC | 1:3 |
| 14-5-23 1:30 | CF Montreal | Toronto FC | 2:0 |
| 14-5-23 1:30 | D.C. United | Nashville SC | 1:1 |
| 14-5-23 1:30 | Inter Miami CF | New England Revolution | 2:1 |
| 14-5-23 1:30 | New York Red Bulls | New York City FC | 1:0 |
| 14-5-23 2:30 | Sporting Kansas City | Minnesota United FC | 3:0 |
| 14-5-23 2:30 | Houston Dynamo | Seattle Sounders | 0:1 |
| 14-5-23 2:30 | Austin FC | FC Dallas | 0:1 |
| 14-5-23 3:30 | Colorado Rapids | Philadelphia Union | 1:2 |
| 14-5-23 3:30 | Real Salt Lake | Los Angeles FC | 0:3 |
| 14-5-23 4:30 | Portland Timbers | Vancouver Whitecaps | 3:1 |
| 15-5-23 3:30 | Los Angeles Galaxy | San Jose Earthquakes | 2:1 |