| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 25-3-23 21:30 | Portland Timbers | Los Angeles Galaxy | 0:0 |
| 26-3-23 0:30 | Charlotte FC | New York Red Bulls | 1:1 |
| 26-3-23 0:30 | D.C. United | New England Revolution | 1:2 |
| 26-3-23 0:30 | Columbus Crew | Atlanta United FC | 6:1 |
| 26-3-23 0:30 | Philadelphia Union | Orlando City | 1:2 |
| 26-3-23 0:30 | Inter Miami CF | Chicago Fire | 2:3 |
| 26-3-23 1:30 | Minnesota United FC | Vancouver Whitecaps | 1:1 |
| 26-3-23 1:30 | Houston Dynamo | New York City FC | 1:0 |
| 26-3-23 1:30 | Austin FC | Colorado Rapids | 1:1 |
| 26-3-23 1:30 | Nashville SC | FC Cincinnati | 0:1 |
| 26-3-23 1:35 | Sporting Kansas City | Seattle Sounders | 1:4 |
| 26-3-23 3:30 | Real Salt Lake | St. Louis City SC | 0:4 |
| 26-3-23 4:30 | San Jose Earthquakes | Toronto FC | 0:0 |
| 26-3-23 4:30 | Los Angeles FC | FC Dallas | 2:1 |