| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 2-12-22 2:15 | New England Patriots | Buffalo Bills | 10:24 |
| 4-12-22 19:00 | Chicago Bears | Green Bay Packers | 19:28 |
| 4-12-22 19:00 | Houston Texans | Cleveland Browns | 14:27 |
| 4-12-22 19:00 | Baltimore Ravens | Denver Broncos | 10:9 |
| 4-12-22 19:00 | Detroit Lions | Jacksonville Jaguars | 40:14 |
| 4-12-22 19:00 | Atlanta Falcons | Pittsburgh Steelers | 16:19 |
| 4-12-22 19:00 | New York Giants | Washington Commanders | 20:20OT |
| 4-12-22 19:00 | Philadelphia Eagles | Tennessee Titans | 35:10 |
| 4-12-22 19:00 | Minnesota Vikings | New York Jets | 27:22 |
| 4-12-22 22:05 | Los Angeles Rams | Seattle Seahawks | 23:27 |
| 4-12-22 22:05 | San Francisco 49ers | Miami Dolphins | 33:17 |
| 4-12-22 22:25 | Cincinnati Bengals | Kansas City Chiefs | 27:24 |
| 4-12-22 22:25 | Las Vegas Raiders | Los Angeles Chargers | 27:20 |
| 5-12-22 2:20 | Dallas Cowboys | Indianapolis Colts | 54:19 |
| 6-12-22 2:15 | Tampa Bay Buccaneers | New Orleans Saints | 17:16 |