| Termijn | Thuis | Uitteam | Uitslag |
|---|---|---|---|
| 23-5-21 17:00 | Aston Villa | FC Chelsea | 2:1 |
| 23-5-21 17:00 | FC Fulham | Newcastle United | 0:2 |
| 23-5-21 17:00 | Leeds United | West Bromwich Albion | 3:1 |
| 23-5-21 17:00 | Manchester City | FC Everton | 5:0 |
| 23-5-21 17:00 | West Ham United | FC Southampton | 3:0 |
| 23-5-21 17:00 | Wolverhampton Wanderers | Manchester United | 1:2 |
| 23-5-21 17:00 | Sheffield United | FC Burnley | 1:0 |
| 23-5-21 17:00 | FC Liverpool | Crystal Palace | 2:0 |
| 23-5-21 17:00 | Leicester City | Tottenham Hotspur | 2:4 |
| 23-5-21 17:00 | FC Arsenal | Brighton and Hove Albion | 2:0 |